Search results for "Transforming Growth Factors"

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The Role of Transforming Growth Factor-β in Human Hepatocarcinogenesis: Mechanistic and Therapeutic Implications From an Integrative Multiomics Appro…

2017

0301 basic medicineCarcinoma HepatocellularHepatologyLiver NeoplasmsGastroenterologyTransforming growth factor betaBiologyArticleCell biology03 medical and health sciences030104 developmental biologyTransforming Growth Factor betaTransforming Growth Factorsbiology.proteinHumansReceptors Transforming Growth Factor betaTransforming growth factorGastroenterology
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Transforming growth factors (TGF-alpha and TGF-beta1) in the determination of vitality and wound age: immunohistochemical study on human skin wounds.

2002

In continuation of former investigations on proinflammatory cytokines, in the present study the relevance of the transforming growth factors TGF-alpha and TGF-beta1 was evaluated for the diagnosis of vitality and wound age. Paraffin sections from human skin wounds due to sharp force influence, which had been collected in operations and autopsies, were investigated using immunohistochemistry. The wound age varied from a few minutes to a maximum of 6 weeks with focus on the early post-traumatic interval up to 5h. Samples from uninjured skin were available as controls. TGF-alpha (n=74) was weakly expressed in normal skin and showed a marked increase in epidermal reactivity after a wound age of…

Blood PlateletsPathologymedicine.medical_specialtyTime Factorsmedicine.medical_treatmentConnective tissueHuman skinPathology and Forensic MedicineProinflammatory cytokineMedicineHumansForensic PathologySkinintegumentary systembusiness.industryGranulation tissueImmunohistochemistryUp-Regulationmedicine.anatomical_structureCytokineConnective tissue metabolismConnective TissueCase-Control StudiesTransforming Growth FactorsImmunohistochemistrybusinessLawBiomarkersTransforming growth factorForensic science international
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